Dr. Sangita Mukhopadhyay received her Ph.D from the Regional Medical Research Centre (ICMR), Bhubaneswar, India. As a graduate student, she worked on immunoregulation in filariasis. She demonstrated that the mode of action of the antifiilarial drug DEC was antibody dependent. DEC cross reacted with one of the filarial glycoprotein. A monoclonal antibody developed against this glycoprotein was found to cross react with DEC, build up a high local concentration of the drug around the parasite to bring about parasite clearance in Mastomys coucha. Later on, as a post-doctoral fellow at the National Institute of immunology, she worked on basic immunology where she demonstrated that the brutons tyrosine kinase (Btk) enzyme affects macrophage effector-APC functions. The Btk was shown to regulate iNOS/NO signaling and there is a cross-talk exists between NO and IL-12. She has also worked on allergen immunology where it has been shown that the delivery of allergen via the scavenger receptors could skew immune response towards Th1 phenotype. Her current research interest is Mycobacterium tuberculosis immunology where she is investigating how various putative virulent proteins help the bacillus in establishing successful infection by counteracting the protective immune responses mounted by the host. Before joining CDFD, she had a brief stint as a staff scientist at the Central Drug Research Institute, Lucknow, India.